Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257140 | 1.00 | TRPA1 (0.35) | TRPA1ATMGABRA1GABRB2CASR | |
| SCHEMBL10548882 | 0.88 | CASR (0.42) | GABRA1GABRB2CASR | |
| SCHEMBL10551320 | 0.86 | TRPA1 (0.36) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL11974108 | 0.84 | GABRA1 (0.33) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL29004016 | 0.79 | GABRA1 (0.30) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL10549419 | 0.77 | CNR1 (0.32) | — | |
| SCHEMBL3418139 | 0.77 | PARP1 (0.35) | — | |
| SCHEMBL2497583 | 0.76 | CASR (0.34) | GABRA1GABRB2CASR | |
| SCHEMBL10548403 | 0.76 | SMN1; SMN2 (0.34) | CASR | |
| SCHEMBL10549035 | 0.76 | TRPA1 (0.35) | TRPA1ATMGABRA1GABRB2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055009-B1 | METHOD FOR PREPARING DEXMEDETOMIDINE | NORCHIM (FR) | 2023-10-11 | — | — | EP | disclosed |
| US-11718586-B2 | Method for preparing dexmedetomidine | NORCHIM (FR) | 2023-08-08 | — | — | US | disclosed |
| US-11718586-B2 | Method for preparing dexmedetomidine | NORCHIM (FR) | 2023-08-08 | — | — | US | disclosed |
| WO-2018087160-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR USE IN CONTROLLING PARASITIC CRUSTACEANS ON FISH | I-TECH AB (SE) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718586-B2 | Method for preparing dexmedetomidine | ADH1C, ADH1A, ADH5 | TRPA1 4517/4885ATM 4147/4885GABRA1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.