Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428766 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27956516 | 0.74 | MEN1 (0.67) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8218393 | 0.72 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8218397 | 0.72 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8218399 | 0.72 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8220485 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8220477 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8220489 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5695413 | 0.68 | MAPT (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5695423 | 0.68 | MAPT (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |