Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428689 | 1.00 | SCN9A (0.44) | SCN9AAKR1C1HPGDTSHRALDH1A1 | |
| SCHEMBL31428758 | 0.84 | PKM (0.50) | AKR1C1HPGDTSHRNPC1RAB9A | |
| SCHEMBL31428637 | 0.82 | HPGD (0.47) | SCN9AHPGDTSHRALDH1A1MAPT | |
| SCHEMBL24975816 | 0.78 | HPGD (0.49) | AKR1C1HPGDNPC1RAB9ALMNA | |
| SCHEMBL31428499 | 0.78 | L3MBTL3 (0.45) | AKR1C1HPGDTSHRL3MBTL3L3MBTL1 | |
| SCHEMBL31428621 | 0.78 | HPGD (0.49) | AKR1C1HPGDNPC1RAB9ALMNA | |
| SCHEMBL31428966 | 0.78 | MEN1 (0.50) | AKR1C1HPGDTSHRL3MBTL1CNR2 | |
| SCHEMBL31428718 | 0.77 | HPGD (0.55) | HPGDTSHRALDH1A1CNR2LMNA | |
| SCHEMBL31428541 | 0.76 | L3MBTL3 (0.57) | SCN9AALDH1A1L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL31428901 | 0.76 | HSD17B10 (0.54) | HPGDALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | SCN9A 3259/4885AKR1C1 802/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.