SCHEMBL24977

SCHEMBL24977

NC(=O)C[C@H](NC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 2/20 0.46
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PTGS1 P23219 1/20 0.40
▸ GSTK1 Q9Y2Q3 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ ITGB2 P05107 2/20 0.39
▸ ICAM1 P05362 2/20 0.39
▸ ITGAL P20701 2/20 0.39
▸ CA2 P00918 4/20 0.38
▸ CA1 P00915 2/20 0.38
▸ OPRM1 P35372 1/20 0.37
▸ OPRD1 P41143 1/20 0.37
▸ OPRK1 P41145 1/20 0.37
▸ PDCD1LG2 Q9BQ51 1/20 0.36
▸ CD274 Q9NZQ7 1/20 0.36
▸ GLO1 Q04760 1/20 0.36
▸ CA4 P22748 1/20 0.36
▸ NOD1 Q9Y239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7454476 0.97 ECE1 (0.43) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL901330 0.97 ECE1 (0.43) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL4803053 0.97 ECE1 (0.43) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL17479551 0.95 ECE1 (0.46) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL2179659 0.95 ECE1 (0.46) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL8145549 0.95 ECE1 (0.46) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL8958919 0.94 ECE1 (0.45) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL6742594 0.93 ECE1 (0.44) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL1487366 0.92 ECE1 (0.46) ECE1MEN1KMT2APTGS1GSTK1
SCHEMBL8710506 0.92 ECE1 (0.43) ECE1MEN1KMT2APTGS1GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12548 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845562-A1 ANTI-PD-1 ANTIBODY AND USE THEREOF Shanghai Junshi Biosciences Co., Ltd. (CN) 2021-07-07 — — EP claimed
US-20210009688-A1 ANTI-PD-1 ANTIBODY AND USE THEREOF SHANGHAI JUNSHI BIOSCIENCES INC. (CN) 2021-01-14 — — US claimed
US-10815302-B2 Anti-PD-1 antibody and use thereof SHANGHAI JUNSHI BIOSCIENCES CO., LTD. (CN) 2020-10-27 — — US claimed
WO-2017190260-A1 VACCINE AGAINST TRYPANOSOMA CRUZI INFECTION FERNANDEZ, Maite (CL) 2017-11-09 — — WO claimed
US-9255150-B2 Remedies for pemphigus containing anti-Fas ligand antibodies PINCELL SRL (IT) 2016-02-09 — — US claimed
EP-2376536-B1 REMEDIES FOR PEMPHIGUS CONTAINING ANTI FAS LIGAND ANTIBODIES PINCELL SRL (IT) 2015-02-25 — — EP claimed
CN-102643348-B Recombinant chimeric protein carrying rotavirus antigen epitope and preparation thereof CHINESE ACAD MED SCIENCE 2014-07-02 — — CN claimed
US-20140086927-A1 NOVEL EPITOPE AND MECHANISM OF ANTIGEN-ANTIBODY INTERACTION IN AN INFLUENZA VIRUS FUJITA HEALTH UNIVERSITY (JP) 2014-03-27 — — US claimed
CN-102643349-B Recombinant chimeric protein carrying hepatitis B virus epitope and preparation thereof CHINESE ACAD MED SCIENCE 2013-12-18 — — CN claimed
CN-103255116-A Scylla paramamosain double-stranded specific deoxyribonuclease as well as preparation method and application thereof UNIV JIMEI 2013-08-21 — — CN claimed
EP-0663956-A1 DNA SEQUENCES WHICH LEAD TO THE FORMATION OF POLYFRUCTANS (LEVANS), PLASMIDS CONTAINING THESE SEQUENCES AS WELL AS A PROCESS FOR PREPARING TRANSGENIC PLANTS Hoechst Schering AgrEvo GmbH (DE) 1995-07-26 — — EP claimed
WO-1994004692-A1 DNA SEQUENCES WHICH LEAD TO THE FORMATION OF POLYFRUCTANS (LEVANS), PLASMIDS CONTAINING THESE SEQUENCES AS WELL AS A PROCESS FOR PREPARING TRANSGENIC PLANTS INSTITUT FÜR GENBIOLOGISCHE FORSCHUNG BERLIN GMBH (DE) 1994-03-03 — — WO claimed
US-5278059-A Oligopeptides KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKI KENKYUJO (JP) 1994-01-11 — — US claimed
EP-0561194-A2 Anti-feline calicivirus recombinant antibody and gene fragment encoding the same Juridical Foundation The Chemo-Sero-Therapeutic Research Institute (JP) 1993-09-22 — — EP claimed
US-5237050-A Proteolytic enzyme inhibitor UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1993-08-17 — — US claimed
EP-0391997-A4 VACCINE — 1992-01-15 — — EP claimed
WO-1991008310-A1 DETECTION OF HUMAN ADENOVIRUS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 — — WO claimed
EP-0391997-A1 VACCINE BIOTECHNOLOGY AUSTRALIA PTY. LTD. (AU) 1990-10-17 — — EP claimed
WO-1990003433-A1 VACCINE BIOTECHNOLOGY AUSTRALIA PTY. LTD. (AU) 1990-04-05 — — WO claimed
CN-1031717-A Be the dna fragmentation of non-A non-B hepatitis coding for antigens specific, contain the expression vector of this dna fragmentation, its transformant and this antigenic method of production MITSUBISHI CHEM IND (JP) 1989-03-15 — — CN claimed
Send feedback