SCHEMBL901330

SCHEMBL901330

NC(=O)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 2/20 0.43
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ PTGS1 P23219 1/20 0.39
▸ GSTK1 Q9Y2Q3 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ ITGB2 P05107 2/20 0.38
▸ ICAM1 P05362 2/20 0.38
▸ ITGAL P20701 2/20 0.38
▸ CA2 P00918 4/20 0.36
▸ CA1 P00915 2/20 0.36
▸ PDCD1LG2 Q9BQ51 1/20 0.35
▸ CD274 Q9NZQ7 1/20 0.35
▸ GLO1 Q04760 1/20 0.34
▸ CA4 P22748 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7454476 1.00 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL24977 0.97 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6742594 0.96 ECE1 (0.44) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8710506 0.94 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL4803053 0.94 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL1443588 0.93 ECE1 (0.44) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL17479551 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL2179659 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8145549 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL9228819 0.92 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002132-A4 90 HUMAN SECRETED PROTEINS HUMAN GENOME SCIENCES INC (US) 2005-04-27 — — EP claimed
EP-1442123-A2 POLYNUCLEOTIDES AND POLYPEPTIDES INVOLVED IN CLAVULINIC ACID BIOSYNTHESIS AND USE THEREOF SMITHKLINE BEECHAM PLC (GB) 2004-08-04 — — EP claimed
WO-2003040372-A2 POLYNUCLEOTIDES AND POLYPEPTIDES INVOLVED IN CLAVULINIC ACID BIOSYNTHESIS AND USE THEREOF SMITHKLINE BEECHAM P.L.C. (GB) 2003-05-15 — — WO claimed
EP-1002132-A1 90 HUMAN SECRETED PROTEINS HUMAN GENOME SCIENCES, INC. (US) 2000-05-24 — — EP claimed
WO-1999007891-A1 90 HUMAN SECRETED PROTEINS HUMAN GENOME SCIENCES, INC. (US) 1999-02-18 — — WO claimed
CN-113754739-B Preparation method and application of coronavirus S protein RBD glycoprotein 上海君实生物医药科技股份有限公司 2024-07-05 — — CN disclosed
CN-109843929-B Proteolytically cleavable chimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2024-07-05 — — CN disclosed
CN-111163809-B Transglutaminase conjugation method and linker 保罗·谢勒学院 2024-07-02 — — CN disclosed
CN-114790465-B Method for improving stability of nano material 中国农业大学 2024-06-28 — — CN disclosed
CN-114652851-B Anti-TROP 2 protein antibody conjugate 石药集团巨石生物制药有限公司 2024-06-07 — — CN disclosed
CN-111201032-B Small-sized group sequence variant of tumor-associated antigen epitope 恩特罗姆公司 2024-05-31 — — CN disclosed
CN-114763552-B Recombinant production method of microbial transglutaminase 山东大学 2024-04-30 — — CN disclosed
WO-1995006737-A1 GLYCOPHORIN BINDING PROTEIN (GBP130) FUSION COMPOSITIONS PRENDERGAST KENNETH FRANCIS (GB) 1995-03-09 — — WO disclosed
WO-1995002675-A1 A DETERGENT COMPOSITION COMPRISING TWO CELLULASE COMPONENTS NOVO NORDISK A/S (DK) 1995-01-26 — — WO disclosed
WO-1994028019-A1 HUMAN CALCIUM SENSOR AAKERSTROEM GOERAN (SE) 1994-12-08 — — WO disclosed
EP-0579709-A1 A PLANT CHITINASE GENE AND USE THEREOF SANDOZ LTD. (CH) 1994-01-26 — — EP disclosed
EP-0510091-A1 AN ENZYME EXHIBITING CELLULASE ACTIVITY. NOVO NORDISK AS (DK) 1992-10-28 — — EP disclosed
WO-1992017591-A1 A PLANT CHITINASE GENE AND USE THEREOF SANDOZ LTD. (CH) 1992-10-15 — — WO disclosed
WO-1992003457-A1 ENTAMOEBA HISTOLYTICA IMMUNODOMINANT SURFACE ANTIGENS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-03-05 — — WO disclosed
WO-1991010732-A1 AN ENZYME EXHIBITING CELLULASE ACTIVITY NOVO NORDISK A/S (DK) 1991-07-25 — — WO disclosed
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