SCHEMBL7454476

SCHEMBL7454476

NC(=O)C[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 2/20 0.43
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ PTGS1 P23219 1/20 0.39
▸ GSTK1 Q9Y2Q3 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ ITGB2 P05107 2/20 0.38
▸ ICAM1 P05362 2/20 0.38
▸ ITGAL P20701 2/20 0.38
▸ CA2 P00918 4/20 0.36
▸ CA1 P00915 2/20 0.36
▸ PDCD1LG2 Q9BQ51 1/20 0.35
▸ CD274 Q9NZQ7 1/20 0.35
▸ GLO1 Q04760 1/20 0.34
▸ CA4 P22748 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901330 1.00 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL24977 0.97 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6742594 0.96 ECE1 (0.44) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8710506 0.94 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL4803053 0.94 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL1443588 0.93 ECE1 (0.44) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL17479551 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL2179659 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8145549 0.93 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL9228819 0.92 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536901-B Antibodies that bind myelin oligodendrocyte glycoprotein 协和麒麟株式会社 2024-06-18 — — CN disclosed
CN-114316047-B PD-1 monoclonal antibodies and medical application thereof 东大生物技术(苏州)有限公司 2023-12-22 — — CN disclosed
US-20230287443-A1 COMPOSITIONS AND METHODS FOR INCREASING PLANT GROWTH AND IMPROVING MULTIPLE YIELD-RELATED TRAITS AFINGEN, INC. (US) 2023-09-14 — — US disclosed
CN-116368233-A Engineered biosynthetic pathway for the production of 4-aminophenylamine by fermentation 齐默尔根公司 2023-06-30 — — CN disclosed
CN-116171168-A Enhancing immune responses by targeting antigen expression 罗特格斯新泽西州立大学 2023-05-26 — — CN disclosed
CN-114272389-B Eribulin-based antibody-drug conjugates and methods of use 卫材研究发展管理有限公司 2023-04-18 — — CN disclosed
US-11613760-B2 Compositions and methods for increasing plant growth and improving multiple yield-related traits AFINGEN, INC. (US) 2023-03-28 — — US disclosed
CN-115772535-A Application of TT2-SCT1/SCT2-WR2 regulation and control pathway in plant heat stress tolerance 中国科学院分子植物科学卓越创新中心 2023-03-10 — — CN disclosed
CN-115209915-A Recruitment of DNA polymerase for templated editing 成对植物服务股份有限公司 2022-10-18 — — CN disclosed
CN-114710957-A Adenovirus vectors and uses thereof 扬森疫苗与预防公司 巴达维亚生物科学公司 爱丁堡大学董事会 尼克拉斯·阿恩伯格咨询公司 2022-07-05 — — CN disclosed
CN-1436234-A Composition and methods for therapy and diagnosis of prostate cancer CORIXA CORP (US) 2003-08-13 — — CN disclosed
EP-0977482-A4 IDENTIFICATION OF POLYNUCLEOTIDES ENCODING NOVEL HELICOBACTER POLYPEPTIDES IN THE HELICOBACTER GENOME MERIEUX ORAVAX (FR) 2002-03-06 — — EP disclosed
CN-1263436-A Identification of polynucleotides encoding novel helicobacter polypeptides in helicobacter genome MERIEUX ORAVAX (FR) 2000-08-16 — — CN disclosed
EP-0977482-A1 IDENTIFICATION OF POLYNUCLEOTIDES ENCODING NOVEL $i(HELICOBACTER) POLYPEPTIDES IN THE $i(HELICOBACTER) GENOME Mérieux Oravax (FR) 2000-02-09 — — EP disclosed
US-6010892-A ANIMAL FEED GIST-BROCADES, B.V. (NL) 2000-01-04 — — US disclosed
US-6001592-A CDNA CODING FOR A NOVEL POLYPEPTIDE MIKIMOTO PHARMACEUTICAL CO., LTD. (JP) 1999-12-14 — — US disclosed
CN-1232087-A Polynucleotide molecules encoding neospora proteins PFIZER PROD INC (US) 1999-10-20 — — CN disclosed
WO-1998043478-A1 IDENTIFICATION OF POLYNUCLEOTIDES ENCODING NOVEL HELICOBACTER POLYPEPTIDES IN THE HELICOBACTER GENOME MERIEUX ORAVAX (FR) 1998-10-08 — — WO disclosed
WO-1998014472-A1 PFS28 FUSION PROTEINS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-04-09 — — WO disclosed
WO-1995008631-A2 TARGET ANTIGENS OF TRANSMISSION BLOCKING ANTIBODIES FOR MALARIA PARASITES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-03-30 — — WO disclosed
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