Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 15/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949344 | 1.00 | MAP3K14 (0.50) | MAP3K14STAT1RORCCA1CA2 | |
| SCHEMBL7421574 | 0.82 | SCN9A (0.58) | STAT1RORC | |
| SCHEMBL16517550 | 0.81 | MAP3K14 (0.66) | MAP3K14STAT1 | |
| SCHEMBL16516967 | 0.81 | MAP3K14 (0.47) | MAP3K14STAT1CA1CA2 | |
| SCHEMBL16517304 | 0.81 | RARG (0.48) | MAP3K14STAT1CA1CA2 | |
| SCHEMBL16516700 | 0.80 | STAT1 (0.49) | MAP3K14STAT1RORC | |
| SCHEMBL16517137 | 0.80 | STAT1 (0.49) | MAP3K14STAT1RORC | |
| SCHEMBL30626340 | 0.80 | KDM4E (0.40) | MAP3K14CA1CA2 | |
| SCHEMBL26074959 | 0.80 | KDM4E (0.40) | MAP3K14CA1CA2 | |
| SCHEMBL4056135 | 0.77 | STAT1 (0.46) | MAP3K14STAT1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | MAP3K14 3706/4885STAT1 3261/4885RORC 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.