SCHEMBL2497787

SCHEMBL2497787

COC(=O)c1ccc(C2=NC(c3ccccc3-c3ccccc3)(C3(c4ccccc4-c4ccccc4)N=C(c4ccc(C(=O)OC)cc4)C(c4ccc(C(=O)OC)cc4)=N3)N=C2c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.52
ALDH1A1 P00352 5/20 0.48
ALDH1A3 P47895 2/20 0.48
ALDH1A2 O94788 1/20 0.48
TSHR P16473 1/20 0.46
SGK1 O00141 1/20 0.46
CAMKK2 Q96RR4 1/20 0.46
PTGS2 P35354 1/20 0.44
PTPN1 P18031 2/20 0.44
PTPRC P08575 1/20 0.44
PTPRF P10586 1/20 0.44
CDC25B P30305 1/20 0.44
PDK2 Q15119 3/20 0.43
SLC2A1 P11166 1/20 0.43
RAB9A P51151 4/20 0.42
MAPT P10636 3/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2496668 0.86 PDK2 (0.50) EGFRALDH1A1TSHRPTPN1PDK2
SCHEMBL2496334 0.86 PARP10 (0.41) EGFRALDH1A1MAPTL3MBTL1SMN1; SMN2
SCHEMBL2955237 0.85 EGFR (0.49) EGFRALDH1A1ALDH1A3ALDH1A2SGK1
SCHEMBL2493563 0.84 TSHR (0.45) EGFRALDH1A1TSHRPTPN1PTPRC
SCHEMBL8663910 0.83 TSHR (0.44) EGFRALDH1A1TSHRPTPN1RAB9A
SCHEMBL8078179 0.83 TSHR (0.44) EGFRALDH1A1TSHRPTPN1PTPRC
SCHEMBL2492082 0.82 TSHR (0.42) EGFRALDH1A1TSHRPTPN1PTPRC
SCHEMBL8668402 0.81 RAB9A (0.48) EGFRALDH1A1TSHRPTPN1PTPRC
SCHEMBL27708108 0.80 EGFR (0.71) EGFRALDH1A1ALDH1A3ALDH1A2TSHR
SCHEMBL8664266 0.80 MAPT (0.41) EGFRALDH1A1TSHRPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10113907-B2 Ultraviolet-sensing sheet, ultraviolet-sensing set, and ultraviolet-sensing method FUJIFILM CORPORATION (JP) 2018-10-30 US disclosed
US-20170131144-A1 ULTRAVIOLET-SENSING SHEET, ULTRAVIOLET-SENSING SET, AND ULTRAVIOLET-SENSING METHOD FUJIFILM CORPORATION (JP) 2017-05-11 US disclosed
US-9068082-B2 Colored curable composition and color filter FUJIFILM CORPORATION (JP) 2015-06-30 US disclosed
US-20150108086-A1 COLORED CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-04-23 US disclosed
US-8029877-B2 Curable resin composition, curable resin composition for forming photosensitive pattern, color filter, liquid crystal panel substrate and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2011-10-04 US disclosed
US-20100238388-A1 CURABLE RESIN COMPOSITION, CURABLE RESIN COMPOSITION FOR FORMING PHOTOSENSITIVE PATTERN, COLOR FILTER, LIQUID CRYSTAL PANEL SUBSTRATE AND LIQUID CRYSTAL PANEL DAI NIPPON PRINTING CO., LTD. (JP) 2010-09-23 US disclosed
US-7537810-B2 Curable resin composition, photosensitive pattern-forming curable resin composition, color filter, substrate for liquid crystalline panel, and liquid crystalline panel DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-26 US disclosed
US-5866298-A Radiation sensitive composition for color filters JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1999-02-02 US disclosed
US-5792589-A ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-08-11 US disclosed
EP-0775941-A1 Radiation sensitive composition for color filters JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-05-28 EP disclosed