Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622351 | 0.80 | LMNA (0.38) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL14838175 | 0.77 | KDM4E (0.43) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL20852892 | 0.76 | CYP3A4 (0.41) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL8291031 | 0.73 | KDM4E (0.37) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL5084622 | 0.72 | TDP1 (0.44) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL29392003 | 0.70 | ALOX5 (0.47) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL87447 | 0.70 | ALOX5 (0.47) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL24936287 | 0.69 | TP53 (0.39) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL11037443 | 0.69 | TDP1 (0.41) | KDM4EMAPTLMNAHTTTP53 | |
| SCHEMBL11352142 | 0.67 | MAPT (0.53) | KDM4EMAPTLMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007426-A1 | NOVEL STYRENE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | PI INDUSTRIES LTD. (IN) | 2023-02-02 | — | — | WO | disclosed |