Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084622 | 0.80 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL87447 | 0.78 | ALOX5 (0.47) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL29392003 | 0.78 | ALOX5 (0.47) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL2602660 | 0.74 | TP53 (0.40) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL16308868 | 0.74 | TDP1 (0.40) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL16308860 | 0.74 | TP53 (0.40) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL685610 | 0.74 | TRPA1 (0.52) | TDP1TP53LMNAMAPTKDM4E | |
| SCHEMBL4598520 | 0.74 | NFE2L2 (0.41) | TDP1TP53CYP1A2CYP2A6LMNA | |
| SCHEMBL11352142 | 0.74 | MAPT (0.53) | TDP1TP53LMNAMAPTKDM4E | |
| SCHEMBL9253034 | 0.74 | ALDH1A1 (0.48) | TDP1TP53CYP1A2CYP2A6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036528-B1 | BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-01-16 | — | — | EP | claimed |