Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24979700 | 1.00 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8DPP7 | |
| SCHEMBL13789959 | 0.84 | SLC7A5 (0.54) | CYP2D6CYP2C19MMP1MMP8HPGD | |
| SCHEMBL15510992 | 0.83 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8DPP7 | |
| SCHEMBL2604879 | 0.83 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8DPP7 | |
| SCHEMBL14577393 | 0.83 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8DPP7 | |
| Hydrochloric Acid SCHEMBL8624053 | 0.83 | SLC7A5 (0.52) | CYP2D6CYP2C19MMP1MMP8HPGD | |
| SCHEMBL14577382 | 0.83 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8DPP7 | |
| Hydrochloric Acid SCHEMBL8624056 | 0.83 | SLC7A5 (0.52) | CYP2D6CYP2C19MMP1MMP8HPGD | |
| SCHEMBL24864654 | 0.81 | DPP7 (0.41) | DPP7DPP4DPP9RRM1 | |
| Hydrochloric Acid SCHEMBL4998926 | 0.81 | CYP2D6 (0.46) | CYP2D6CYP2C19MMP1MMP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | NPPA, LNPEP, CLPP | CYP2D6 4358/4885CYP2C19 4280/4885MMP1 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.