Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185106 | 0.91 | CRHR1 (0.48) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL24984517 | 0.91 | CRHR1 (0.48) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL30185102 | 0.91 | PTGES (0.42) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL24984519 | 0.91 | PTGES (0.42) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL30185245 | 0.89 | CRHR1 (0.47) | CRHR1P2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24986581 | 0.89 | CRHR1 (0.47) | CRHR1P2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30185287 | 0.85 | AKR1C3 (0.42) | SMN1; SMN2TAS1R3TAS1R1CTSA | |
| SCHEMBL24984463 | 0.85 | AKR1C3 (0.42) | SMN1; SMN2TAS1R3TAS1R1CTSA | |
| SCHEMBL24985641 | 0.85 | MAPT (0.43) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL30185318 | 0.85 | MAPT (0.43) | SMN1; SMN2MAPTNPC1RAB9ACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | SMN1; SMN2 3265/4885MAPT 3017/4885NPC1 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.