Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185254 | 1.00 | ADORA2A (0.39) | ADORA2ASTIM1ORAI1ORAI2FFAR4 | |
| SCHEMBL30185085 | 0.88 | P2RX7 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL30185184 | 0.88 | STIM1 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL24984538 | 0.88 | STIM1 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL24984542 | 0.88 | P2RX7 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL24984539 | 0.87 | P2RX7 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL30185118 | 0.87 | P2RX7 (0.35) | ADORA2ASTIM1ORAI1ORAI2CSNK1E | |
| SCHEMBL24984449 | 0.86 | ALDH1A1 (0.37) | STIM1ORAI1ORAI2NPC1RAB9A | |
| SCHEMBL30185232 | 0.86 | ALDH1A1 (0.37) | STIM1ORAI1ORAI2NPC1RAB9A | |
| SCHEMBL24986967 | 0.85 | CSNK1E (0.35) | STIM1ORAI1ORAI2CSNK1ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | ADORA2A 689/4885STIM1 3677/4885ORAI1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.