Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24985379 | 0.86 | LMNA (0.53) | KLK1KLK5MAPTGFERLMNA | |
| SCHEMBL31185288 | 0.80 | RXFP1 (0.40) | RXFP1MAPTGFERLMNAGRM2 | |
| SCHEMBL24985483 | 0.80 | RXFP1 (0.40) | RXFP1MAPTGFERLMNAGRM2 | |
| SCHEMBL24985188 | 0.78 | LMNA (0.54) | RXFP1MAPTGFERLMNAGRM2 | |
| SCHEMBL24984225 | 0.76 | LMNA (0.64) | MAPTGFERLMNAGRM2SMN1; SMN2 | |
| SCHEMBL24985451 | 0.74 | LMNA (0.54) | MAPTGFERLMNAGRM2RAB9A | |
| SCHEMBL30163836 | 0.74 | LMNA (0.56) | RXFP1MAPTGFERLMNAGRM2 | |
| SCHEMBL24985409 | 0.71 | GRM2 (0.53) | MAPTGFERLMNAGRM2SMN1; SMN2 | |
| SCHEMBL24985186 | 0.71 | LMNA (0.49) | MAPTGFERLMNAGRM2SMN1; SMN2 | |
| SCHEMBL30164100 | 0.71 | LMNA (0.49) | MAPTGFERLMNAGRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006893-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN, IN PARTICULAR NEUROPATHIC PAIN, AND/OR OTHER DISEASES OR DISORDERS THAT ARE ASSOCIATED WITH AT2R AND/OR AT2R MEDIATED SIGNALING | CONFO THERAPEUTICS N.V. (BE) | 2023-02-02 | — | — | WO | disclosed |