Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192057 | 1.00 | RAB9A (0.33) | RAB9AMAPTALDH1A1L3MBTL1GABRA1 | |
| SCHEMBL6006591 | 0.82 | FFAR1 (0.37) | RAB9AMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL6006594 | 0.82 | FFAR1 (0.37) | RAB9AMAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL2493751 | 0.76 | MAPT (0.37) | RAB9AMAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11664002 | 0.70 | MAPT (0.52) | RAB9AMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL2459013 | 0.70 | MAPT (0.52) | RAB9AMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL2459012 | 0.70 | MAPT (0.52) | RAB9AMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL2464131 | 0.70 | MAPT (0.52) | RAB9AMAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL1306384 | 0.70 | GABRA1 (0.38) | RAB9AMAPTALDH1A1GABRA1GABRG2 | |
| SCHEMBL12192055 | 0.70 | CYP2D6 (0.51) | RAB9AMAPTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030482-B2 | 3-beta-tetrahydropyranyloxy-22-[4-(4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)butyroxy]-23-bisnorchol-5-ene, used in fluorescence spectroscopy for monitoring exchange, distribution and trafficking of cholesterol between living cells and lipid domains in membranes | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2011-10-04 | — | — | US | disclosed |
| US-20080177059-A1 | FREE CHOLESTEROL ANALOGS BEARING A BORON DIPYRROMETHENE DIFLUORO (BODIPY) FLUOROPHORE IN THE SIDE CHAIN AND METHOD OF PREPARATION AND USE THEREOF | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177059-A1 | FREE CHOLESTEROL ANALOGS BEARING A BORON DIPYRROMETHENE DIFLUORO (BODIPY) FLUOROPHORE IN THE SIDE CHAIN AND METHOD OF PREPARATION AND USE THEREOF | NPC1L1, CETP, NPC1 | RAB9A 747/4885MAPT 1365/4885ALDH1A1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.