SCHEMBL24988641

SCHEMBL24988641

CCCCc1cc(CCCCCCN)c2[nH]c(-c3ccccc3)cc2c1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 13/20 0.42
CTSV O60911 2/20 0.39
CTSL P07711 2/20 0.39
MPL P40238 2/20 0.39
MAOA P21397 1/20 0.38
PSMB5 P28074 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24989505 1.00 TLR8 (0.42) TLR8CTSVCTSLMPLMAOA
SCHEMBL24988933 0.99 TLR8 (0.41) TLR8CTSVCTSLMPLMAOA
SCHEMBL24989577 0.88 TLR8 (0.39) TLR8MPL
SCHEMBL24988650 0.85 CTSV (0.45) CTSVCTSLMPLPSMB5
SCHEMBL24990242 0.81 CTSV (0.44) CTSVCTSLMPLPSMB5
SCHEMBL24989524 0.80 MPL (0.39) CTSVCTSLMPL
SCHEMBL24988907 0.79 PSMB5 (0.44) CTSVCTSLMPLPSMB5
SCHEMBL24988657 0.78 CTSV (0.43) CTSVCTSLMPLPSMB5
SCHEMBL24989519 0.76 MPL (0.41) CTSVCTSLMPLPSMB5
SCHEMBL24988939 0.75 MPL (0.43) CTSVCTSLMPLPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013994-A1 NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-02-09 WO disclosed