Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988907 | 0.96 | PSMB5 (0.44) | CTSVCTSLHSD11B1GPR84NPY5R | |
| SCHEMBL25014429 | 0.90 | NPY5R (0.42) | NPY5RPPARGNPC1RAB9AADORA3 | |
| SCHEMBL24990242 | 0.84 | CTSV (0.44) | CTSVCTSLHSD11B1GPR84NPY5R | |
| SCHEMBL25014995 | 0.82 | NPY5R (0.39) | GPR84NPY5RPPARGNPC1RAB9A | |
| SCHEMBL24988650 | 0.81 | CTSV (0.45) | CTSVCTSLGPR84NPY5RPSMB5 | |
| SCHEMBL24989519 | 0.79 | MPL (0.41) | CTSVCTSLHSD11B1GPR84NPY5R | |
| SCHEMBL24988856 | 0.79 | NPY5R (0.42) | CTSVCTSLNPY5RPSMB5MPL | |
| SCHEMBL24988933 | 0.79 | TLR8 (0.41) | CTSVCTSLPSMB5MPL | |
| SCHEMBL24988939 | 0.78 | MPL (0.43) | CTSVCTSLHSD11B1GPR84NPY5R | |
| SCHEMBL24988943 | 0.78 | PPARG (0.58) | CTSVCTSLGPR84PPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |