Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988641 | 0.99 | TLR8 (0.42) | TLR8MPLCTSVCTSLMAOA | |
| SCHEMBL24989505 | 0.99 | TLR8 (0.42) | TLR8MPLCTSVCTSLMAOA | |
| SCHEMBL24989577 | 0.87 | TLR8 (0.39) | TLR8MPL | |
| SCHEMBL24988650 | 0.86 | CTSV (0.45) | MPLCTSVCTSLPSMB5 | |
| SCHEMBL24989524 | 0.81 | MPL (0.39) | MPLCTSVCTSL | |
| SCHEMBL24988907 | 0.80 | PSMB5 (0.44) | MPLCTSVCTSLPSMB5 | |
| SCHEMBL24990242 | 0.79 | CTSV (0.44) | MPLCTSVCTSLPSMB5 | |
| SCHEMBL24988657 | 0.79 | CTSV (0.43) | MPLCTSVCTSLPSMB5 | |
| SCHEMBL24989519 | 0.77 | MPL (0.41) | MPLCTSVCTSLPSMB5 | |
| SCHEMBL24988939 | 0.76 | MPL (0.43) | MPLCTSVCTSLPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |