Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | CTSV | O60911 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827129 | 0.83 | PPARG (0.66) | PPARGCTSVCTSLCYP19A1NPC1 | |
| SCHEMBL10513486 | 0.83 | CTSV (0.68) | CTSVCTSLNPC1RAB9AKDM4E | |
| SCHEMBL8998711 | 0.83 | CTSV (0.68) | CTSVCTSLNPC1RAB9AKDM4E | |
| SCHEMBL24990239 | 0.81 | FFAR1 (0.48) | PPARGCTSVCTSLNPC1RAB9A | |
| SCHEMBL27821692 | 0.79 | CTSV (0.67) | CTSVCTSLCYP19A1NPC1RAB9A | |
| SCHEMBL24988657 | 0.78 | CTSV (0.43) | PPARGCTSVCTSLNPC1RAB9A | |
| SCHEMBL16382883 | 0.77 | PPARG (0.70) | PPARGCYP19A1NPC1RAB9AKDM4E | |
| SCHEMBL1461108 | 0.77 | GHSR (0.47) | CTSVCTSLKDM4EKMT2AALDH1A1 | |
| SCHEMBL865468 | 0.77 | HTR1A (0.43) | CTSVCTSLKDM4EMAPTALDH1A1 | |
| SCHEMBL28323119 | 0.77 | PPARG (0.66) | PPARGCYP19A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |