Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988674 | 0.88 | MPL (0.41) | NPY5RCYP1A1TAAR1ALDH1A1HPGD | |
| SCHEMBL30224906 | 0.81 | ALDH1A1 (0.38) | NPY5RCYP1A1TAAR1ALDH1A1HPGD | |
| SCHEMBL24989509 | 0.74 | NPY5R (0.43) | NPY5RALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL30182788 | 0.71 | NPY5R (0.40) | NPY5RALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL27237615 | 0.70 | NPY5R (0.42) | NPY5RALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL24989577 | 0.70 | TLR8 (0.39) | TAAR1TLR8 | |
| SCHEMBL24990242 | 0.70 | CTSV (0.44) | NPY5R | |
| SCHEMBL30182792 | 0.69 | NPY5R (0.39) | NPY5RKDM4EMAPTMEN1KMT2A | |
| SCHEMBL30182862 | 0.68 | NPY5R (0.40) | NPY5RKDM4EMAPTMEN1KMT2A | |
| SCHEMBL25014981 | 0.68 | NPY5R (0.40) | NPY5RALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |