Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988673 | 0.88 | NPY5R (0.39) | TLR8NPY5RCYP1A1TAAR1ALDH1A1 | |
| SCHEMBL24989577 | 0.82 | TLR8 (0.39) | MPLTLR8TAAR1GCGR | |
| SCHEMBL24990242 | 0.81 | CTSV (0.44) | MPLNPY5RCTSVCTSLGPR84 | |
| SCHEMBL24990239 | 0.79 | FFAR1 (0.48) | CYP1A1ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL24989509 | 0.78 | NPY5R (0.43) | NPY5RALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL30224906 | 0.77 | ALDH1A1 (0.38) | NPY5RCYP1A1TAAR1ALDH1A1LMNA | |
| SCHEMBL24988682 | 0.74 | MPL (0.39) | MPLTLR8ALDH1A1HPGDKDM4E | |
| SCHEMBL30182908 | 0.73 | NPY5R (0.39) | NPY5RKDM4EMAPT | |
| SCHEMBL24989606 | 0.73 | ADK (0.40) | MPLTLR8ALDH1A1HPGDKDM4E | |
| SCHEMBL3161897 | 0.72 | TAAR1 (0.50) | TLR8TAAR1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |