Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294836 | 0.91 | CYP1A2 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4973094 | 0.88 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28426885 | 0.85 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6683046 | 0.83 | SELL (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28733526 | 0.83 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL75798 | 0.83 | ALDH1A1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL207494 | 0.83 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL578127 | 0.83 | CLCN2 (0.56) | GABRA1GABRB2CLCN2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17911667 | 0.82 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15821394 | 0.82 | GABRA1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281078-A | POLYESTERS AND HYDROXYALKYL ACRYLATE POLYMERS CURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| WO-2023216732-A1 | CHEMICAL SYNTHESIS METHOD FOR HELICOBACTER PYLORI CORE LIPOPOLYSACCHARIDE OLIGOSACCHARIDE ANTIGEN CARBOHYDRATE CHAIN | 江南大学 | 2023-11-16 | — | — | WO | disclosed |
| WO-2020162414-A1 | STABILIZING AGENT COMPOSITION, VINYL CHLORIDE RESIN COMPOSITION CONTAINING SAME AND MOLDED BODY THEREOF | 株式会社ADEKA | 2020-08-13 | — | — | WO | disclosed |
| US-9051473-B2 | Clear coating compositions comprising dispersed silica nono-particles and processes for using | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-8974898-B2 | Coated substrate having enhanced scratch and mar resistance | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-03-10 | — | — | US | disclosed |
| US-8030513-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100204376-A1 | Rheology Control Agents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2010-08-12 | — | — | US | disclosed |
| US-7741510-B2 | Rheology control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1846516-B1 | RHEOLOGY CONTROL AGENTS FOR COATING COMPOSITIONS | DU PONT (US) | 2010-04-07 | — | — | EP | disclosed |
| US-7652121-B2 | Containing urea, ester, terminal hydroxy groups; provides rheology control without deteriorating appearance, durability or weatherability of high solids and low solids coating compositions that are often used in automotive and truck manufacturing and to refinish or repaint automobile bodies | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-4504620-A | ADHESION PROMOTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4482609-A | SEALERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| US-4471083-A | AUTOMOTIVE FINISHES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| US-4442256-A | AUTOMOBILE TOP COATINGS, HARDNESS, GLOSS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| US-4346201-A | COATINGS FOR FLEXIBLE SUBSTRATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4338379-A | HYDROXYL SUBSTITUTED ACRYLIC POLYMER, PENTAERYTHRITOL-TYPE POLYESTER CURED BY AN AMINOPLAST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4316940-A | BLENDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-23 | — | — | US | disclosed |
| US-4281078-A | POLYESTERS AND HYDROXYALKYL ACRYLATE POLYMERS CURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4147674-A | Aqueous coating composition of an acrylic-vinyl oxazoline ester polymer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4020216-A | Coating composition for flexible substrates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204376-A1 | Rheology Control Agents | HCRTR1, HCRTR2, REL | GABRP 3106/4885GABRD 1897/4885GABRA1 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.