Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24989037 | 0.84 | KDM4E (0.58) | DRD2DRD3TP53HRH3HTR3E | |
| SCHEMBL30855584 | 0.82 | DRD2 (1.00) | DRD2DRD3CYP1A2CYP3A4HTR7 | |
| SCHEMBL249732 | 0.82 | DRD2 (1.00) | DRD2DRD3CYP1A2CYP3A4HTR7 | |
| Hydrochloric Acid SCHEMBL6408589 | 0.81 | DRD2 (0.97) | DRD2DRD3CYP1A2CYP3A4HTR7 | |
| Hydrochloric Acid SCHEMBL6494513 | 0.81 | DRD2 (0.97) | DRD2DRD3CYP1A2CYP3A4HTR7 | |
| Hydrochloric Acid SCHEMBL29882147 | 0.81 | DRD2 (0.97) | DRD2DRD3CYP1A2CYP3A4HTR7 | |
| SCHEMBL24409797 | 0.79 | ACVR1 (0.74) | — | |
| SCHEMBL1359864 | 0.78 | ADRB1 (0.76) | CYP1A2CYP3A4HTR7HTR1ATP53 | |
| SCHEMBL6956744 | 0.78 | KDM4E (0.63) | DRD2DRD3LMNATP53HTR3E | |
| SCHEMBL231077 | 0.78 | KDM4E (0.63) | DRD2DRD3LMNATP53HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011596-A1 | AMIDE COMPOUND AND USE THEREOF | 中国药科大学 | 2023-02-09 | — | — | WO | disclosed |