SCHEMBL24990789

SCHEMBL24990789

c1ccc(-c2cccc3oc4ccccc4c23)c(-c2nc(-c3cccc4c3ccc3ccc5ccccc5c34)nc(-c3cccc4c3sc3ccccc34)n2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PRKDC P78527 7/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
ALOX5 P09917 1/20 0.34
PARP14 Q460N5 1/20 0.32
MAPT P10636 2/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23821953 0.92 ALOX5 (0.37) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL26435292 0.90 L3MBTL1 (0.41) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL25525303 0.89 ALOX5 (0.38) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL24990523 0.88 ALOX5 (0.37) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL24990785 0.87 ALOX5 (0.39) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL24991426 0.86 ALOX5 (0.38) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL25843874 0.84 TDP1 (0.40) L3MBTL1TDP1MAPTBRDTALDH1A1
SCHEMBL23822546 0.84 ALOX5 (0.39) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL24991411 0.84 ALOX5 (0.38) L3MBTL1TDP1PRKDCPIK3CDPIK3CB
SCHEMBL24991532 0.83 L3MBTL1 (0.47) L3MBTL1TDP1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023014190-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-02-09 WO disclosed