SCHEMBL26435292

SCHEMBL26435292

c1ccc2c(c1)ccc1cccc(-c3nc(-c4cccc5c4sc4ccccc45)nc(-c4cccc5oc6ccccc6c45)n3)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX5 P09917 1/20 0.37
PRKDC P78527 7/20 0.37
PIK3CD O00329 2/20 0.37
PIK3CB P42338 2/20 0.37
PARP14 Q460N5 1/20 0.35
MAPT P10636 4/20 0.34
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 4/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24990789 0.90 L3MBTL1 (0.40) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL26435298 0.90 ALOX5 (0.43) L3MBTL1ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL26434985 0.90 PRKDC (0.39) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL25525303 0.89 ALOX5 (0.38) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL23821953 0.88 ALOX5 (0.37) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL26435266 0.88 TDP1 (0.40) L3MBTL1TDP1MAPTBRDTKDM4E
SCHEMBL26435283 0.87 ALOX5 (0.42) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL24657620 0.87 ALOX5 (0.43) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL26047495 0.87 ALOX5 (0.40) L3MBTL1TDP1ALOX5PRKDCPIK3CD
SCHEMBL23822547 0.87 ALOX5 (0.40) L3MBTL1TDP1ALOX5PRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 L3MBTL1 1536/4885TDP1 1017/4885ALOX5 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.