SCHEMBL24992425

SCHEMBL24992425

CCc1cc(N)ccc1NCCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 2/20 0.43
ALDH1A1 P00352 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HRH3 Q9Y5N1 1/20 0.39
BRD4 O60885 1/20 0.38
ATAD2 Q6PL18 1/20 0.38
ACP1 P24666 1/20 0.38
SLC2A1 P11166 1/20 0.37
PRKCI P41743 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.36
ALOX12 P18054 1/20 0.36
PAX8 Q06710 1/20 0.36
RAD52 P43351 1/20 0.36
HTT P42858 1/20 0.36
ACHE P22303 1/20 0.36
NQO2 P16083 1/20 0.36
MALT1 Q9UDY8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15585982 0.81 NCF1 (0.47) NCF1ALDH1A1NPSR1HRH3BRD4
SCHEMBL6815177 0.80 ALDH1A1 (0.49) NCF1ALDH1A1NPSR1HRH3BRD4
SCHEMBL1444351 0.80 PRKCI (0.39) ALDH1A1BRD4PRKCIMAPTHTT
SCHEMBL24992452 0.80 JAK2 (0.36) ALDH1A1PRKCIMAPTHTTACHE
SCHEMBL7929760 0.79 MAPT (0.46) ALDH1A1PRKCISMN1; SMN2MAPTHTT
SCHEMBL30885131 0.79 NQO2 (0.42) MAPTNQO2
SCHEMBL9024554 0.79 NCF1 (0.44) NCF1ALDH1A1NPSR1HRH3BRD4
SCHEMBL12005700 0.77 PRKCI (0.37) NCF1ALDH1A1HRH3PRKCIMAPT
SCHEMBL24900467 0.76 NCF1 (0.43) NCF1ALDH1A1NPSR1MAPTALOX12
SCHEMBL3935349 0.76 ALDH1A1 (0.39) NCF1ALDH1A1NPSR1BRD4ATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023011610-A1 BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 南京红云生物科技有限公司 2023-02-09 WO disclosed