Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.37 |
| ▸ | INSR | P06213 | 4/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993672 | 0.92 | PTK2 (0.35) | BRD4EGFRSTK17AALKAXL | |
| SCHEMBL24993662 | 0.88 | MAPK9 (0.48) | BRD4EGFRALKMAPK9MAPK10 | |
| SCHEMBL24992458 | 0.86 | BRD4 (0.54) | BRD4EGFRALKAXL | |
| SCHEMBL24993090 | 0.85 | BRD4 (0.44) | BRD4EGFRALKMETMAPK9 | |
| SCHEMBL24992488 | 0.81 | EGFR (0.53) | BRD4EGFRALKMETINSR | |
| SCHEMBL24993688 | 0.80 | STK17A (0.44) | BRD4EGFRSTK17BSTK17AALK | |
| SCHEMBL24993689 | 0.80 | ALK (0.42) | BRD4EGFRSTK17BSTK17AALK | |
| SCHEMBL24992461 | 0.79 | ALK (0.43) | BRD4EGFRSTK17BSTK17AALK | |
| SCHEMBL24993046 | 0.78 | FLT3 (0.48) | BRD4EGFRFLT3 | |
| SCHEMBL24993663 | 0.78 | EGFR (0.48) | BRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |