Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30168278 | 0.99 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNACRHBPCRHR2 | |
| SCHEMBL25001991 | 0.75 | ADRA1D (0.33) | ALDH1A1MAPK1LMNAMAPTSMN1; SMN2 | |
| Bromide SCHEMBL962929 | 0.75 | HDAC3 (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL29339719 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPK1LMNACRHBPCRHR2 | |
| SCHEMBL18295094 | 0.71 | F2RL3 (0.56) | ALDH1A1MAPK1LMNACRHBPCRHR2 | |
| SCHEMBL1562627 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1MAPK1LMNACRHBPCRHR2 | |
| SCHEMBL27677805 | 0.71 | CRHBP (0.56) | ALDH1A1MAPK1LMNACRHBPCRHR2 | |
| SCHEMBL23727916 | 0.71 | TSHR (0.58) | ALDH1A1MAPK1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11557647 | 0.71 | ALDH1A1 (0.60) | ALDH1A1LMNACRHBPCRHR2F2RL3 | |
| SCHEMBL15848888 | 0.71 | EPHX2 (0.57) | ALDH1A1MAPK1LMNACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |