Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | INMT | O95050 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749749 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL23749754 | 0.74 | ALDH1A1 (0.42) | TDP1ALDH1A1KMT2ALMNACYP2D6 | |
| SCHEMBL30130841 | 0.74 | INMT (0.36) | ALDH1A1KMT2AHCAR1INMT | |
| SCHEMBL23749772 | 0.74 | INMT (0.36) | ALDH1A1KMT2AHCAR1INMT | |
| SCHEMBL25001926 | 0.71 | KMT2A (0.43) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL23749750 | 0.70 | GAA (0.46) | TDP1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL23727071 | 0.69 | INMT (0.41) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL9226972 | 0.68 | TDP1 (0.36) | TDP1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL5664153 | 0.66 | MAPT (0.47) | TDP1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL12572956 | 0.64 | TDP1 (0.45) | TDP1ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |