Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002592 | 0.90 | MEN1 (0.42) | MEN1KMT2ADRD2DRD3OPRM1 | |
| SCHEMBL25003075 | 0.79 | INMT (0.39) | MEN1KMT2ADRD2DRD3FGFR1 | |
| SCHEMBL10386947 | 0.78 | SIGMAR1 (0.54) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL25001896 | 0.78 | ADRB1 (0.46) | MEN1KMT2ADRD2DRD3NPC1 | |
| Bromide SCHEMBL10800477 | 0.77 | SIGMAR1 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL25001894 | 0.69 | GAA (0.38) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28643385 | 0.68 | MEN1 (0.55) | MEN1KMT2ADRD2DRD3OPRM1 | |
| SCHEMBL25001981 | 0.68 | SIGMAR1 (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL25003073 | 0.68 | INMT (0.32) | MEN1KMT2AALDH1A1HSD17B10INMT | |
| SCHEMBL25002137 | 0.68 | INMT (0.32) | INMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |