Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885790 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTGPR119TLR9 | |
| SCHEMBL27237976 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5374374 | 0.84 | STS (0.49) | LMNAMAPTGPR119ALDH1A1MAPK8 | |
| SCHEMBL28714527 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMAPTGPR119TLR9 | |
| SCHEMBL14653337 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2LMNAMAPTGPR119ALDH1A1 | |
| SCHEMBL14852499 | 0.76 | MEN1 (0.56) | SMN1; SMN2LMNAMAPTGPR119ALDH1A1 | |
| SCHEMBL30208139 | 0.76 | MEN1 (0.56) | SMN1; SMN2LMNAMAPTGPR119ALDH1A1 | |
| SCHEMBL246696 | 0.75 | DRD2 (0.56) | LMNAMAPTALDH1A1MAPK8MEN1 | |
| SCHEMBL5364792 | 0.75 | STS (0.49) | LMNAMAPTGPR119ALDH1A1MAPK8 | |
| SCHEMBL31219913 | 0.74 | GPR119 (0.52) | SMN1; SMN2LMNAMAPTGPR119TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769545-A | Tri-fused ring derivative-containing regulator, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |