Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003570 | 0.84 | KMO (0.50) | KMT2AMEN1KMOSCN10ASUCNR1 | |
| SCHEMBL25003146 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1KMOKDM4EGAA | |
| SCHEMBL25003151 | 0.82 | ALDH1A1 (0.57) | KMT2AMEN1KMOSCN10AADORA3 | |
| SCHEMBL25003132 | 0.80 | CYP2D6 (0.50) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25003143 | 0.80 | MEN1 (0.48) | KMT2AMEN1KMOKDM4EGAA | |
| SCHEMBL25003141 | 0.80 | KMO (0.48) | KMT2AMEN1KMOKDM4EGAA | |
| SCHEMBL25003825 | 0.80 | SCN10A (0.68) | KMT2AMEN1SCN10AADORA3KDM4E | |
| SCHEMBL25003139 | 0.78 | KMO (0.68) | KMT2AMEN1KMOKDM4EGAA | |
| SCHEMBL25003803 | 0.78 | SUCNR1 (0.67) | SCN10ASUCNR1SCN2AABL1 | |
| SCHEMBL30489168 | 0.78 | MEN1 (0.69) | KMT2AMEN1KMOSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |