Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FOS | P01100 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711389 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASYKMAPT | |
| SCHEMBL4715139 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASYKMAPT | |
| SCHEMBL29508799 | 0.82 | ALDH1A1 (0.54) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL25003607 | 0.82 | ALDH1A1 (0.54) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL22860433 | 0.82 | ALDH1A1 (0.54) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL16094578 | 0.82 | ALDH1A1 (0.41) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL30560100 | 0.82 | ALDH1A1 (0.41) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL4715488 | 0.82 | ALDH1A1 (0.41) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL30498445 | 0.82 | ALDH1A1 (0.41) | RAB9AALDH1A1MEN1KMT2ASYK | |
| SCHEMBL4760645 | 0.81 | MEN1 (0.41) | RAB9AALDH1A1MEN1KMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230042936-A1 | PYRIDO[2,3-d]PYRIMIDIN-7(8H)-ONES AS CDK INHIBITORS | FUNDACION DEL SECTOR PUBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (F.S.P. CNIO) (ES) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230042936-A1 | PYRIDO[2,3-d]PYRIMIDIN-7(8H)-ONES AS CDK INHIBITORS | CDK7, CDK8, CDK9 | RAB9A 1872/4885ALDH1A1 967/4885EPHX2 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.