Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249529 | 0.84 | ALDH1A1 (0.41) | TDP1HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17905231 | 0.84 | TDP1 (0.47) | TDP1HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL487272 | 0.83 | TDP1 (0.47) | TDP1ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL895988 | 0.83 | TDP1 (0.47) | TDP1ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL19427363 | 0.80 | LMNA (0.49) | TDP1CYP3A4ALDH1A1MAPTATM | |
| SCHEMBL27646116 | 0.80 | TDP1 (0.40) | TDP1CYP1A2CYP2C19ALDH1A1FAAH | |
| SCHEMBL17377676 | 0.79 | LMNA (0.51) | TDP1ALDH1A1LPAR1LPAR3MAPT | |
| SCHEMBL11111869 | 0.79 | TDP1 (0.44) | TDP1TLR2ALDH1A1USP2KDM4E | |
| SCHEMBL887703 | 0.79 | TDP1 (0.44) | TDP1TLR2ALDH1A1USP2KDM4E | |
| SCHEMBL503413 | 0.79 | TDP1 (0.44) | TDP1TLR2ALDH1A1USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038642-A1 | ALDIMINES AND USES THEREOF | BOSTIK SA (FR) | 2023-02-09 | — | — | US | disclosed |