Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31646292 | 0.86 | EPHX2 (0.46) | POLBMEN1KMT2APDK2EPHX2 | |
| SCHEMBL3872255 | 0.86 | EPHX2 (0.46) | POLBMEN1KMT2APDK2EPHX2 | |
| SCHEMBL19532816 | 0.86 | CA2 (0.41) | MAPTSMN1; SMN2LMNAGALR3STAT3 | |
| SCHEMBL23591206 | 0.82 | SOS1 (0.36) | MAPTSMN1; SMN2LMNAGALR3STAT3 | |
| SCHEMBL25477881 | 0.81 | POLB (0.47) | MAPTSMN1; SMN2LMNAGALR3STAT3 | |
| SCHEMBL5514195 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL24341933 | 0.77 | EPHX2 (0.37) | MAPTSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL19533102 | 0.74 | CA2 (0.46) | MEN1KMT2AALDH1A1TDP1NPSR1 | |
| SCHEMBL8311149 | 0.72 | PTGES2 (0.40) | MAPTPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9882817 | 0.72 | GABRA1 (0.43) | PDK2ALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011540-A1 | FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 苏州信诺维医药科技股份有限公司 | 2023-02-09 | — | — | WO | disclosed |