Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 9/20 | 0.38 |
| ▸ | MAOA | P21397 | 8/20 | 0.38 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993587 | 0.81 | ALDH1A1 (0.41) | MAPTKDM1AMAOAMAOBHRH3 | |
| SCHEMBL8025619 | 0.70 | KDM1A (0.51) | KIF11KDM1AMAOAMAOBCYP2D6 | |
| SCHEMBL8037056 | 0.70 | KDM1A (0.51) | KIF11KDM1AMAOAMAOBCYP2D6 | |
| SCHEMBL12030746 | 0.69 | HRH3 (0.50) | KIF11KDM1ACYP2D6HRH3KCNH2 | |
| SCHEMBL23993572 | 0.68 | ALDH1A1 (0.41) | MAPTHRH3ALDH1A1 | |
| SCHEMBL9939164 | 0.68 | RIPK1 (0.38) | TSHRSMN1; SMN2KDM1AMAOAMAOB | |
| SCHEMBL18334117 | 0.67 | KIF11 (0.44) | SMN1; SMN2KIF11KDM1ACYP2D6HRH3 | |
| SCHEMBL1415636 | 0.67 | KDM1A (0.54) | KDM1AMAOAMAOB | |
| SCHEMBL25004859 | 0.66 | — | — | |
| SCHEMBL25004857 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | MAPT 4826/4885TSHR 2272/4885SMN1; SMN2 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.