Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004715 | 0.81 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL25005545 | 0.78 | HRH3 (0.43) | CHRNA7KDM1AMAOBCHRNB2CHRNA4 | |
| SCHEMBL25004743 | 0.77 | KDM1A (0.43) | KDM1AMAOBMAOAPPARGPPARD | |
| SCHEMBL24867535 | 0.75 | KDM1A (0.40) | KDM1AMAOBCHRNB2CHRNA4MAOA | |
| SCHEMBL25897312 | 0.73 | KDM1A (0.37) | CHRNA7KDM1ACHRNB2CHRNA4SSTR4 | |
| SCHEMBL25005431 | 0.72 | PDE10A (0.36) | PPARGPPARDPPARA | |
| SCHEMBL25004312 | 0.72 | KDM1A (0.31) | KDM1AMAOB | |
| SCHEMBL30224944 | 0.71 | LIPE (0.33) | CHRNA7 | |
| SCHEMBL23993597 | 0.70 | KDM1A (0.38) | CHRNA7KDM1ACHRNB2CHRNA4MAOA | |
| SCHEMBL25004988 | 0.70 | ALOX5 (0.45) | KDM1APPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | CHRNA7 1915/4885KDM1A 2052/4885MAOB 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.