Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653250 | 0.82 | SMN1; SMN2 (0.47) | HPGDLMNAMAPTGAAHTT | |
| SCHEMBL25636403 | 0.82 | PGR (0.43) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL18653070 | 0.79 | SMN1; SMN2 (0.36) | HPGDLMNAMAPTGAAHTT | |
| SCHEMBL23468155 | 0.77 | RAB9A (0.43) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL21212233 | 0.77 | NPC1 (0.53) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL18653233 | 0.76 | MAPT (0.35) | HPGDLMNAMAPTGAAALDH1A1 | |
| SCHEMBL18653128 | 0.76 | SMN1; SMN2 (0.34) | HPGDLMNAMAPTGAAALDH1A1 | |
| SCHEMBL18653224 | 0.75 | SMN1; SMN2 (0.35) | HPGDLMNAMAPTGAAHTT | |
| SCHEMBL14350992 | 0.73 | RAB9A (0.53) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL22641356 | 0.70 | RAB9A (0.50) | PGRSCN1ASCN2ASCN3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |