Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MYOC | Q99972 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653128 | 0.93 | SMN1; SMN2 (0.34) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18653070 | 0.86 | SMN1; SMN2 (0.36) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18653224 | 0.84 | SMN1; SMN2 (0.35) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18653152 | 0.77 | GAA (0.33) | GAASMN1; SMN2HPGD | |
| SCHEMBL18653130 | 0.77 | RIPK1 (0.35) | LMNAGAASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL18653238 | 0.77 | LMNA (0.35) | MAPTALDH1A1LMNATAS1R3TAS1R1 | |
| SCHEMBL25006760 | 0.76 | PGR (0.47) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18653163 | 0.75 | GAA (0.34) | GAASMN1; SMN2HPGD | |
| SCHEMBL18653243 | 0.74 | SMN1; SMN2 (0.47) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18653250 | 0.74 | SMN1; SMN2 (0.47) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |