SCHEMBL25006853

SCHEMBL25006853

C[C@H](CO)C[C@@H]1CCNC1=O

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6732243 0.82 AR (0.44) PTGER3
SCHEMBL24963632 0.82 CCR2 (0.35) PTGER3
SCHEMBL25134397 0.80 CTSL (0.39)
SCHEMBL25134408 0.80 CTSL (0.39)
SCHEMBL25134614 0.79 PTGER3 (0.35) PTGER3
SCHEMBL30009270 0.79 CAPN1 (0.36)
SCHEMBL25761980 0.79 CAPN1 (0.36)
SCHEMBL23866547 0.78 CTSL (0.32)
SCHEMBL24754822 0.78 CTSL (0.32)
SCHEMBL24754817 0.78 CTSL (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11859014-B2 Peptidomimetics for the treatment of Norovirus infection EMORY UNIVERSITY (US) 2024-01-02 US disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 US disclosed
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-25 US disclosed
WO-2023014758-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. (US) 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION VIM, ACE, ACE2 PTGER3 4715/4885
US-11859014-B2 Peptidomimetics for the treatment of Norovirus infection VIP, HAVCR2, NGLY1 PTGER3 3005/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 PTGER3 1593/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 PTGER3 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.