Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PLAAT5 | Q96KN8 | 8/20 | 0.60 |
| ▸ | PLAAT4 | Q9UL19 | 8/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 7/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 7/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163215 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL22412530 | 0.83 | PLAAT5 (0.75) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL1027805 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL7858 | 0.80 | KDM4E (0.69) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL4831685 | 0.80 | PLAAT5 (0.70) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL22145183 | 0.79 | PLAAT5 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL1197319 | 0.79 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL6175376 | 0.79 | CYP1A2 (0.70) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL31736052 | 0.78 | KDM4E (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL3379087 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |