Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24007479 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP3A4KDM4EEPHX2ALDH1A1 | |
| SCHEMBL15984372 | 0.84 | OPRL1 (0.36) | ALDH1A1CYP2C19CYP2D6TSHRCYP1A2 | |
| SCHEMBL14670913 | 0.82 | MEN1 (0.38) | SMN1; SMN2ALDH1A1CYP2D6CYP1A2HRH3 | |
| SCHEMBL14670918 | 0.81 | CYP2C9 (0.48) | CYP3A4ALDH1A1CYP2C19CYP2D6TSHR | |
| SCHEMBL16375282 | 0.80 | JAK3 (0.35) | HRH3 | |
| SCHEMBL18256186 | 0.79 | CYP3A4 (0.43) | CYP3A4KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL23240355 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP3A4KDM4EEPHX2ALDH1A1 | |
| SCHEMBL14671004 | 0.78 | OPRM1 (0.33) | KDM4EHRH3 | |
| SCHEMBL24574461 | 0.77 | CYP2C9 (0.40) | CYP3A4KDM4EEPHX2ALDH1A1MAPK1 | |
| SCHEMBL22200882 | 0.77 | HPGD (0.39) | SMN1; SMN2EPHX2ALDH1A1MAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827639-B2 | TDO2 and IDO1 inhibitors | GENENTECH, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827639-B2 | TDO2 and IDO1 inhibitors | IDO1, TDO2, IDO2 | SMN1; SMN2 3994/4885CYP3A4 428/4885KDM4E 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.