Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23707472 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL21757030 | 0.86 | OPRM1 (0.43) | SMN1; SMN2ALDH1A1MAPK1CYP2C19CYP3A4 | |
| SCHEMBL25157111 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL15987021 | 0.82 | ALDH1A1 (0.33) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL25009341 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL15986907 | 0.79 | CYP2C9 (0.44) | ALDH1A1CYP2C19CYP3A4HIF1ACYP2C9 | |
| SCHEMBL15987022 | 0.79 | MEN1 (0.37) | SMN1; SMN2ALDH1A1HSD17B10NPC1 | |
| SCHEMBL21078057 | 0.78 | CYP3A4 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL21134521 | 0.78 | CYP3A4 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1CYP2C19 | |
| SCHEMBL21756991 | 0.77 | CHRM4 (0.40) | ALDH1A1CHRM4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| WO-2021068953-A1 | SUBSTITUTED TRICYCLIC COMPOUND AS PRMT5 INHIBITOR AND USE THEREOF | 南京圣和药业股份有限公司 | 2021-04-15 | — | — | WO | disclosed |