Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009655 | 0.89 | PIN1 (0.46) | MAPK14PIN1TP53SMN1; SMN2AURKA | |
| SCHEMBL23416147 | 0.76 | MAPK14 (0.41) | MAPK14PIN1TP53SMN1; SMN2NR1I2 | |
| SCHEMBL23416280 | 0.74 | MAPK14 (0.40) | MAPK14PIN1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL25009200 | 0.74 | MAPT (0.52) | TP53SMN1; SMN2CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL25009392 | 0.72 | ALDH1A1 (0.42) | NR1I2CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL23736199 | 0.66 | TP53 (0.65) | TP53SMN1; SMN2AURKANR1I2CYP1A2 | |
| SCHEMBL31679074 | 0.66 | TP53 (0.65) | TP53SMN1; SMN2AURKANR1I2CYP1A2 | |
| SCHEMBL23758270 | 0.66 | AURKA (0.55) | PIN1TP53SMN1; SMN2AURKANR1I2 | |
| SCHEMBL25010505 | 0.65 | ALDH1A1 (0.40) | MAPK14TP53SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL7795648 | 0.65 | MAPK14 (0.67) | MAPK14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230041576-A1 | METHODS AND MATERIALS FOR INHIBITING NF-kB ACTIVITY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230041576-A1 | METHODS AND MATERIALS FOR INHIBITING NF-kB ACTIVITY | NFKBIA, IKBKB, NFKB2 | MAPK14 1716/4885PIN1 2017/4885TP53 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.