Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886976 | 0.79 | POLB (0.45) | POLBMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL30124712 | 0.79 | POLB (0.45) | POLBMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL17193044 | 0.77 | ALDH1A1 (0.45) | POLBMAPTALDH1A1GAAMAPK1 | |
| SCHEMBL31211070 | 0.77 | NOS3 (0.39) | POLBMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15894463 | 0.77 | NR4A2 (0.46) | POLBMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3886713 | 0.77 | POLB (0.53) | POLBALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL29513014 | 0.77 | POLB (0.53) | POLBALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL29672030 | 0.77 | NR4A2 (0.46) | POLBMAPTALDH1A1MAPK1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL415501 | 0.76 | POLB (0.52) | POLBALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL15819409 | 0.74 | POLB (0.46) | POLBMAPTALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |