SCHEMBL25009792

SCHEMBL25009792

Fc1cccc(-c2cccc3cccc(Br)c23)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
PIK3R1 P27986 1/20 0.43
PIK3CA P42336 1/20 0.43
RELA Q04206 1/20 0.40
TAAR1 Q96RJ0 2/20 0.39
ESR2 Q92731 1/20 0.39
NT5E P21589 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 2/20 0.36
UBE2N P61088 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAOB P27338 1/20 0.36
CDC7 O00311 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28862846 0.81 MAOB (0.42) KDM4EHPGDRXFP1MEN1MAPT
SCHEMBL25009794 0.81 KDR (0.42) HPGDNPSR1PIK3R1PIK3CAMEN1
SCHEMBL31408657 0.81 MAPK1 (0.58) KDM4EHPGDNPSR1RXFP1PIK3R1
SCHEMBL3564382 0.81 MAPK1 (0.58) KDM4EHPGDNPSR1RXFP1PIK3R1
SCHEMBL15457919 0.79 MAPK1 (0.60) KDM4EHPGDNPSR1RELAMEN1
SCHEMBL29961643 0.79 MAPK1 (0.60) KDM4EHPGDNPSR1RELAMEN1
SCHEMBL28818819 0.78 MAPK1 (0.48) KDM4EHPGDNPSR1RXFP1PIK3R1
SCHEMBL29315480 0.77 FYN (0.52) KDM4EHPGDTAAR1ESR2MEN1
SCHEMBL29315474 0.76 TAAR1 (0.62) KDM4EHPGDTAAR1ESR2NT5E
SCHEMBL25009764 0.75 ALDH1A1 (0.44) KDM4EHPGDNPSR1RXFP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-07-18 US disclosed
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-07-18 US disclosed
WO-2023011028-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS AOX1, AOC2, OSTC KDM4E 2309/4885HPGD 2568/4885NPSR1 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.