SCHEMBL2501100

SCHEMBL2501100

[CH2]COCCOCC(=C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2499820 0.90 CES2 (0.34)
SCHEMBL631462 0.89 HSD17B10 (0.37) THRBHSD17B10TDP1
SCHEMBL367825 0.86
SCHEMBL29488236 0.86 MEN1 (0.35) THRBHSD17B10TDP1
SCHEMBL347964 0.86 MEN1 (0.35) THRBHSD17B10TDP1
SCHEMBL22042688 0.82 THRB (0.30) THRB
SCHEMBL42380 0.81
SCHEMBL13498373 0.79
SCHEMBL30054587 0.79 CES2 (0.37) THRBHSD17B10TDP1
SCHEMBL10885420 0.79 THRB (0.50) THRBHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084217-B1 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2020-07-22 EP disclosed
US-8030415-B2 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2011-10-04 US disclosed
US-20100204409-A1 Process For Crosslinking Thermoplastic Polymers With Silanes Employing Peroxide Blends, The Resulting Crosslinked Thermoplastic Polymer Composition And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 US disclosed
EP-2084217-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-08-05 EP disclosed
WO-2008060508-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-22 WO disclosed
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US disclosed