Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | GRK2 | P25098 | 2/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250873 | 0.91 | PLAAT3 (0.58) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL23111915 | 0.86 | MCHR1 (0.50) | TAAR1CNR1ALDH1A1KMT2A | |
| SCHEMBL26988416 | 0.86 | PLAAT3 (0.54) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Phenethylcarbamic Acid SCHEMBL12478843 | 0.84 | SMN1; SMN2 (0.59) | TAAR1HTR2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL14672313 | 0.81 | HSP90AA1 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL915701 | 0.80 | ESRRG (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4RAB9A | |
| SCHEMBL16443753 | 0.80 | KMT2A (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL5840627 | 0.79 | CNR1 (0.54) | TAAR1HTR2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL25303812 | 0.78 | CNR1 (0.66) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5261796 | 0.78 | MTNR1A (0.51) | TAAR1HTR2APLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |