Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.58 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LIG1 | P18858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26988416 | 0.94 | PLAAT3 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL250129 | 0.91 | TAAR1 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL14672313 | 0.89 | HSP90AA1 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL16443753 | 0.88 | KMT2A (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL25303812 | 0.86 | CNR1 (0.66) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL3236518 | 0.84 | CA12 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL5840627 | 0.82 | CNR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL553085 | 0.82 | KDM4E (0.70) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL5840621 | 0.82 | CNR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL26988011 | 0.82 | MTNR1A (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | disclosed |
| EP-4368625-A1 | SHP2 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-05-15 | — | — | EP | disclosed |
| EP-3992177-B1 | DERIVATIVE COMPOUND INTRODUCING BIPHENYL GROUP INTO NOVEL AMINOALKANOIC ACID AND ANTIFUNGAL PHARMACEUTICAL COMPOSITION COMPRISING SAME | AMTIXBIO CO LTD (KR) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024091498-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| EP-4268811-A1 | NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME | Amtixbio Co., Ltd. (KR) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023132353-A1 | METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUPS | 中外製薬株式会社 | 2023-07-13 | — | — | WO | disclosed |
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |
| US-20230067422-A1 | AMINOALKANOIC ACID DERIVATIVE CONTAINING BIPHENYL GROUP AND USE OF THE SAME | AMTIXBIO CO., LTD. (KR) | 2023-03-02 | — | — | US | disclosed |
| EP-2119703-A1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-18 | — | — | EP | disclosed |
| US-20090005353-A1 | Non-Anilinic Derivatives of Isothiazol-3(2H)-one 1,1-Dioxides as Liver X Receptor Modulators | ASTRAZENECA AB (SE) | 2009-01-01 | — | — | US | disclosed |
| EP-1962855-A2 | TRPA1 INHIBITORS FOR TREATING PAIN | Hydra Biosciences, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1838687-A1 | NON-ANILINIC DERIVATIVES OF ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AS LIVER X RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2007073505-A2 | TRPA1 INHIBITORS FOR TREATING PAIN | HYDRA BIOSCIENCES, INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006073366-A1 | NON-ANILINIC DERIVATIVES OF ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AS LIVER X RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |
| EP-1590321-A2 | ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY | Sanofi-Aventis (FR) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004067498-A2 | ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY | SANOFI-AVENTIS (FR) | 2004-08-12 | — | — | WO | disclosed |
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005353-A1 | Non-Anilinic Derivatives of Isothiazol-3(2H)-one 1,1-Dioxides as Liver X Receptor Modulators | NR1H2, NR1H3, NR1I2 | PLAAT3 1257/4885PLAAT5 1583/4885PLAAT2 1010/4885 |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | PTPN1, PTPN5, PTPN2 | PLAAT3 499/4885PLAAT5 404/4885PLAAT2 611/4885 |
| US-20230067422-A1 | AMINOALKANOIC ACID DERIVATIVE CONTAINING BIPHENYL GROUP AND USE OF THE SAME | GABBR1, AADAC, GABBR2 | PLAAT3 308/4885PLAAT5 546/4885PLAAT2 506/4885 |
| US-12029739-B2 | SHP2 inhibitor and use thereof | PTPN1, PTPN5, PTPN2 | PLAAT3 499/4885PLAAT5 404/4885PLAAT2 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.