SCHEMBL25014155

SCHEMBL25014155

O=P1(Oc2ccc3ccccc3c2)OCC(CBr)(CBr)CO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
NPC1 O15118 3/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
AGXT P21549 2/20 0.35
PTPN7 P35236 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARG P37231 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13816566 0.85 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2
SCHEMBL13816563 0.84 MAPK1 (0.35) HSD17B10KMT2AMAPK1TDP1
SCHEMBL25014156 0.82 PPARG (0.33) ALDH1A1HPGDNPC1RAB9APPARG
SCHEMBL13697353 0.81 ALDH1A1 (0.42) ALOX5ALDH1A1HSD17B10HPGDALOX15
SCHEMBL13697354 0.80 CETP (0.38) ALOX5ALDH1A1HSD17B10HPGDALOX15
SCHEMBL25014153 0.77 HTR1B (0.36) ALDH1A1HSD17B10HPGDRAB9AKMT2A
SCHEMBL25014893 0.75 CYP3A4 (0.33) ALDH1A1HSD17B10HPGDALOX15MAOA
SCHEMBL25014160 0.74 TSHR (0.34) ALDH1A1MAOAMAOBAGXTKMT2A
SCHEMBL25014158 0.71 SMN1; SMN2 (0.32) SMN1; SMN2KDM4E
SCHEMBL12669990 0.65 RECQL (0.41) HSD17B10KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007982-A1 PHOSPHORUS COMPOUND HAVING ISOCYANURATE RING, SYNTHETIC METHOD THEREFOR, AND USE OF SAID PHOSPHORUS COMPOUND HAVING ISOCYANURATE RING 四国化成工業株式会社 2023-02-02 WO disclosed